What is HCG?
Human Chorionic Gonadotropin (HCG) is a natural hormone produced by the placenta and purified from the urine of pregnant women. The action of HCG is virtually identical to that of pituitary LH as it triggers ovulation.

Are there side effects to HCG?
The following adverse reactions have been associated with administration of HCG: headache, irritability, restlessness, fatigue, breast tenderness and nausea.

Can HCG affect the developing fetus?
There is no increased risk of an abnormality from that reported in the general population.

What is Suprefact?
Lupron/Suprefact acts on the pituitary gland. This medication causes suppression of the ovarian response, unless the ovary has been stimulated with other drugs such as Puregon or Gonal F.

What are the side effects of Suprefact?
The following adverse reactions have been associated with administration of Lupron/Suprefact: joint pain, headache, hot flashes, bruising and tenderness around the injection site.

Can Lupron/Suprefact affect the developing fetus?
In comparison with the general population, there is no increased risk of an abnormality.

What is Gonal F/Puregon?
Both of these medications are made from highly purified human Follicle Stimulating Hormone prepared by recombinant DNA technology. Both are non-urinary products and contains only FSH. There is no LH component.

Are there any side effects to Gonal F/Puregon?
Some women experience abdominal discomfort, headache, weight gain, irritability and breast tenderness. The most serious side effect is ovarian hyperstimulation. Hyperstimulation occurs when many follicles develop in response to Gonal F/Puregon stimulation. This causes sudden enlargement of the ovary and the abdomen may become distended with fluid. Hyperstimulation is usually mild to moderate. However, severe hyperstimulation occurs in 1-3% of patients. Treatment consists of bed rest and careful monitoring of fluid levels.

Can Gonal F/Puregon affect the developing fetus?
There is no increased risk of an abnormality from that reported in the general population.